FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MX1
反应性
Human,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 500-580
特异性
MX1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
MX1
蛋白名称
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Organism-1
Human
基因ID-1
4599
SwissProt-1
P20591
Organism-2
Mouse
SwissProt-2
P09922
Organism-3
Rat
SwissProt-3
P18588
背景
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
细胞定位
Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, perinuclear region . Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845). .; [Isoform 2]: Cytoplasm . Nucleus . Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636). .
