FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CP46A
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
CP46A Polyclonal Antibody detects endogenous levels of protein.
基因名称
CYP46A1 CYP46
蛋白名称
Cholesterol 24-hydroxylase (CH24H) (Cytochrome P450 46A1)
Organism-1
Human
基因ID-1
10858
SwissProt-1
Q9Y6A2
Organism-2
Mouse
SwissProt-2
Q9WVK8
背景
cytochrome P450 family 46 subfamily A member 1(CYP46A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse . Cell projection, dendrite .
