- 产品信息
商品描述
靶点-Target
NR2C1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
66kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
NR2C1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
NR2C1 TR2
蛋白名称
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)
Organism-1
Human
基因ID-1
7181
SwissProt-1
P13056
Organism-2
Mouse
SwissProt-2
Q505F1
Organism-3
Rat
SwissProt-3
Q8VIJ4
背景
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, PML body . Recruited by HDAC3, after all-trans retinoic acid stimulated MAPK1-mediated Thr-223 phosphorylation, to PML bodies for subsequent sumoylation. .





