FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PDE3A
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
125kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 250-330
特异性
PDE3A Polyclonal Antibody detects endogenous levels of protein.
基因名称
PDE3A
蛋白名称
cGMP-inhibited 3',5'-cyclic phosphodiesterase A (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)
Organism-1
Human
基因ID-1
5139
SwissProt-1
Q14432
Organism-2
Mouse
SwissProt-2
Q9Z0X4
Organism-3
Rat
SwissProt-3
Q62865
背景
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Membrane ; Multi-pass membrane protein . Cytoplasm, cytosol .
