- 产品信息
商品描述
靶点-Target
BCL3
反应性
Human,Rat,Mouse,Goat
应用
IHC,IF,WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
WB 1:500-2000;IF 1:50-200;IHC 1:50-300
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 340-420
特异性
BCL3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
BCL3 BCL4 D19S37
蛋白名称
B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Organism-1
Human
基因ID-1
602
SwissProt-1
P20749
Organism-2
Mouse
SwissProt-2
Q9Z2F6
背景
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .





