FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TLR5
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
94kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 730-810
特异性
TLR5 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TLR5 TIL3
蛋白名称
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Organism-1
Human
基因ID-1
7100
SwissProt-1
O60602
Organism-2
Mouse
SwissProt-2
Q9JLF7
背景
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
