ATX3 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2602213

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商品描述
  • 靶点-Target

    Ataxin-3

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    40kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 200-280

  • 特异性

    ATX3 Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    ATXN3 ATX3 MJD MJD1 SCA3

  • 蛋白名称

    Ataxin-3 (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)

  • Organism-1

    Human

  • 基因ID-1

    4287

  • SwissProt-1

    P54252

  • Organism-2

    Mouse

  • SwissProt-2

    Q9CVD2

  • Organism-3

    Rat

  • SwissProt-3

    O35815

  • 背景

    ataxin 3(ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016],

  • 细胞定位

    Nucleus matrix . Nucleus . Predominantly nuclear, but not exclusively, inner nuclear matrix.