Cytokeratin 8&18 (ABT053/CK18) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602192

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商品描述
  • 靶点-Target

    Cytokeratin 8/18

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    48kD,54kD

  • 推荐稀释比

    IHC 1:200-400;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT053/CK18

  • 免疫原

    Synthesized peptide derived from human Cytokeratin 8&18 AA range: C-term to CK8 and 200-300 to CK18

  • 特异性

    This product can specifically recognize human CK8 and CK18 protein. It is a cocktail of anti-CK8 and anti-CK18 monoclonal antibodies.

  • 基因名称

    KRT8/KRT18

  • Organism-1

    Human

  • 基因ID-1

    3856;3875

  • SwissProt-1

    P05787;P05783

  • 背景

    keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

  • 细胞定位

    Cytoplasmic, Membranous