FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
S100
反应性
Human,Mouse,Rat,
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
11kD
推荐稀释比
IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT094
免疫原
Synthesized peptide derived from human S100 AA range: 2-92
特异性
The antibody can specifically recognize human S100B protein, and has a weak reaction with S100A1, but no cross reaction with S100A4 or S100A6.
基因名称
S100B
蛋白名称
S100
别名
Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B;
Organism-1
Human
基因ID-1
6285
SwissProt-1
P04271
背景
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy
细胞定位
Nuclear, Cytoplasmic
