FGF-2 Polyclonal Antibody
¥680.00
PMEL/Melanoma gp100 (HMB45) (ABT255) Mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2602186
- 产品信息
商品描述
靶点-Target
HMB45
反应性
Human,Mouse,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
70kD
MW(Observed)
80kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT255
免疫原
Synthesized peptide derived from human PMEL AA range: 400-500
特异性
The antibody can specifically recognize human PMEL protein.
基因名称
PMEL D12S53E PMEL17 SILV
蛋白名称
95 kDa melanocyte specific secreted glycoprotein;95 kDa melanocyte-specific secreted glycoprotein;D12S53E;gp100;M-beta;ME20;ME20 M/ME20 S;ME20-M;ME20-S;ME20M;ME20M/ME20S;ME20S;Melanocyte lineage specific antigen GP100;Melanocyte protein mel 17;Melanocyte protein Pmel 17;Melanocyte protein Pmel 17 precursor;Melanocytes lineage-specific antigen GP100;Melanoma associated ME20 antigen;Melanoma gp100;Melanoma-associated ME20 antigen;Melanosomal matrix protein 17;Melanosomal matrix protein17;P1;p100;p26;PMEL 17;PMEL;PMEL_HUMAN;PMEL17;Premelanosome protein;Secreted melanoma-associated ME20 antigen;SI;SIL;SILV;Silver (mouse homolog) like;Silver homolog;Silver locus protein homolog;Silver, mouse, homolog of
别名
95 kDa melanocyte specific secreted glycoprotein;95 kDa melanocyte-specific secreted glycoprotein;D12S53E;gp100;M-beta;ME20;ME20 M/ME20 S;ME20-M;ME20-S;ME20M;ME20M/ME20S;ME20S;Melanocyte lineage specific antigen GP100;Melanocyte protein mel 17;Melanocyte protein Pmel 17;Melanocyte protein Pmel 17 precursor;Melanocytes lineage-specific antigen GP100;Melanoma associated ME20 antigen;Melanoma gp100;Melanoma-associated ME20 antigen;Melanosomal matrix protein 17;Melanosomal matrix protein17;P1;p100;p26;PMEL 17;PMEL;PMEL_HUMAN;PMEL17;Premelanosome protein;Secreted melanoma-associated ME20 antigen;SI;SIL;SILV;Silver;mouse homolog;like;Silver homolog;Silver locus protein homolog;HMB45;
Organism-1
Human
SwissProt-1
P40967
Organism-2
Mouse
SwissProt-2
Q60696
背景
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],
细胞定位
Cytoplasmic
