- 产品信息
商品描述
靶点-Target
Glypican-3
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
66kD
MW(Observed)
58kD
推荐稀释比
IHC 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT180
免疫原
Synthesized peptide derived from human Glypican-3(GPC3) AA range: 400-500
特异性
The antibody can specifically recognize human Glypican-3 protein.
基因名称
GPC3 OCI5
蛋白名称
Glypican-3(GPC3)
别名
Glypican-3;GTR2-2;Intestinal protein OCI-5;MXR7;[Cleaved into: Secreted glypican-3]
Organism-1
Human
基因ID-1
2719
SwissProt-1
P51654
背景
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
细胞定位
Cytoplasmic





