Glypican-3 (ABT068) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602172

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商品描述
  • 靶点-Target

    Glypican-3

  • 反应性

    Human,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    66kD

  • MW(Observed)

    58kD

  • 推荐稀释比

    IHC 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT068

  • 免疫原

    Synthesized peptide derived from human Glypican-3(GPC3) AA range: 400-500

  • 特异性

    The antibody can specifically recognize human Glypican-3 protein.

  • 基因名称

    GPC3 OCI5

  • 蛋白名称

    Glypican-3(GPC3)

  • 别名

    Glypican-3;GTR2-2;Intestinal protein OCI-5;MXR7;[Cleaved into: Secreted glypican-3]

  • Organism-1

    Human

  • 基因ID-1

    2719

  • SwissProt-1

    P51654

  • 背景

    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],

  • 细胞定位

    Cytoplasmic