- 产品信息
商品描述
靶点-Target
Vimentin
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
53kD
MW(Observed)
54kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT281
免疫原
Synthesized peptide derived from human Vimentin AA range: 400-466
特异性
The antibody can specifically recognize human Vimentin protein.
基因名称
VIM
蛋白名称
Vimentin
别名
Vimentin
Organism-1
Human
基因ID-1
7431
SwissProt-1
P08670
背景
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],
细胞定位
Cytoplasmic





