- 产品信息
商品描述
靶点-Target
PSA
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
28kD
MW(Observed)
28kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT114
免疫原
Synthesized peptide derived from human PSA AA range: 100-200
特异性
The antibody can specifically recognize human PSA protein.
基因名称
KLK3 APS
蛋白名称
PSA
别名
Prostate-specific antigen;PSA;Gamma-seminoprotein;Seminin;Kallikrein-3;P-30 antigen;Semenogelase;
Organism-1
Human
基因ID-1
354
SwissProt-1
P07288
背景
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic





