- 产品信息
商品描述
靶点-Target
NF-L
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
68kD
MW(Observed)
68kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT456
免疫原
Synthesized peptide derived from human Neurofilament AA range: 400-543
特异性
The antibody can specifically recognize human Neurofilament protein, especilaly NF-L protein.
基因名称
NEFL NF68 NFL
蛋白名称
Neurofilament
别名
Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein;
Organism-1
Human
基因ID-1
4747
SwissProt-1
P07196
背景
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],
细胞定位
Cytoplasmic





