FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Factor XIIIa
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
76kD,83kD
MW(Observed)
83kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT170
免疫原
Synthesized peptide derived from human Factor XIIIa AA range: 400-500
特异性
The antibody can specifically recognize human Factor XIIIa protein.
基因名称
F13A1 F13A
蛋白名称
Factor XIIIa
别名
Coagulation factor XIII A chain;Coagulation factor XIIIa;Protein-glutamine gamma-glutamyltransferase A chain;Transglutaminase A chain;
Organism-1
Human
基因ID-1
2162
SwissProt-1
P00488
背景
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or
细胞定位
Cytoplasmic
