CD3 (ABT295) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

一键复制产品信息
产品规格:
  • 50μL
货号:

FAB2602123

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    CD3E

  • 反应性

    Human,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    23kD

  • MW(Observed)

    23kD

  • 推荐稀释比

    IHC 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT295

  • 免疫原

    Synthesized peptide derived from human CD3, CD3E AA range: 1-100

  • 特异性

    The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g.

  • 基因名称

    CD3E T3E

  • 蛋白名称

    CD3, CD3E

  • 别名

    T-cell surface glycoprotein CD3 epsilon chain;T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e;

  • Organism-1

    Human

  • 基因ID-1

    916

  • SwissProt-1

    P07766

  • 背景

    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membranous