- 产品信息
商品描述
靶点-Target
CD3E
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
23kD
MW(Observed)
23kD
推荐稀释比
IHC 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT295
免疫原
Synthesized peptide derived from human CD3, CD3E AA range: 1-100
特异性
The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g.
基因名称
CD3E T3E
蛋白名称
CD3, CD3E
别名
T-cell surface glycoprotein CD3 epsilon chain;T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e;
Organism-1
Human
基因ID-1
916
SwissProt-1
P07766
背景
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],
细胞定位
Membranous





