- 产品信息
商品描述
靶点-Target
CD141
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
62kD
MW(Observed)
100kD
推荐稀释比
IHC 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT145
免疫原
Synthesized peptide derived from human CD141 AA range: 50-150
特异性
The antibody can specifically recognize human CD141 protein.
基因名称
THBD THRM
蛋白名称
CD141
别名
Thrombomodulin;TM;Fetomodulin;CD antigen CD141;
Organism-1
Human
基因ID-1
7056
SwissProt-1
P07204
背景
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],
细胞定位
Membranous





