- 产品信息
商品描述
靶点-Target
Caldesmon
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
93kD
MW(Observed)
93kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT125
免疫原
Synthesized peptide derived from human Caldesmon pan AA range: 100-200
特异性
The antibody can recognize human h-caldesmon and l-caldesmon protein.
基因名称
CALD1 CAD CDM
蛋白名称
Caldesmon pan
别名
Caldesmon;CDM;
Organism-1
Human
基因ID-1
800
SwissProt-1
Q05682
背景
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic





