- 产品信息
商品描述
靶点-Target
Arginase I
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
35kD
MW(Observed)
37kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-Arg1
免疫原
Synthesized peptide derived from human Arginase-1 AA range: 200-322
特异性
The antibody can specifically recognize human Arginase-1 protein.
基因名称
ARG1
蛋白名称
Arginase-1 (Liver-type arginase) (Type I arginase)
Organism-1
Human
基因ID-1
383
SwissProt-1
P05089
背景
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Nuclear, Cytoplasmic





