Beta-catenin (ABT-Catenin) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2602094
- 产品信息
商品描述
靶点-Target
Catenin-β
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
84kD
MW(Observed)
94kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-Catenin
免疫原
Synthesized peptide derived from human Beta-catenin AA range: 700-781
特异性
The antibody can specifically recognize human β- Catenin protein.
基因名称
CTNNB1 CTNNB OK/SW-cl.35 PRO2286
蛋白名称
Catenin-β;b-catenin;Beta catenin;Beta-catenin;Cadherin associated protein;Catenin (cadherin associated protein), beta 1, 88 kDa;Catenin beta 1;Catenin beta-1;CATNB;CHBCAT;CTNB1_HUMAN;CTNNB;CTNNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289
别名
CTNNB1;CTNNB;OK/SW-cl.35;Catenin beta-1;Beta-catenin
Organism-1
Human
基因ID-1
1499
SwissProt-1
P35222
背景
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
细胞定位
Membranous





