FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TIMP1
反应性
Human,
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
23kD
MW(Observed)
23kD
推荐稀释比
IHC 1:50-200.IF 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-TIMP1
免疫原
Synthesized peptide derived from human Tissue Inhibitor of Metalloproteinases 1(TIMP1) AA range: 50-150
特异性
This antibody detects endogenous levels of TIMP1 protein.
基因名称
TIMP1 CLGI TIMP
蛋白名称
Tissue Inhibitor of Metalloproteinases 1(TIMP1)
Organism-1
Human
基因ID-1
7076
SwissProt-1
P01033
背景
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic
