AMACR (ABT-AMACR) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602086

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商品描述
  • 靶点-Target

    AMACR

  • 反应性

    Human,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    42kD

  • MW(Observed)

    42kD

  • 推荐稀释比

    IHC 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-AMACR

  • 免疫原

    Synthesized peptide derived from human AMACR AA range: 300-382

  • 特异性

    The antibody can specifically recognize human AMACR protein.

  • 基因名称

    AMACR

  • 蛋白名称

    AMACR

  • Organism-1

    Human

  • 基因ID-1

    23600

  • SwissProt-1

    Q9UHK6

  • 背景

    This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],

  • 细胞定位

    Cytoplasmic