Mast cell tryptase (PT2024) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602084

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商品描述
  • 靶点-Target

    Mast cell tryptase

  • 反应性

    Human,

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    30kD

  • MW(Observed)

    30kD

  • 推荐稀释比

    IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT2024

  • 免疫原

    Synthesized peptide derived from human Mast cell tryptase AA range: 200-275

  • 特异性

    The antibody can specifically recognize human Mast cell tryptase protein.

  • 基因名称

    TPSAB1 TPS1 TPS2 TPSB1

  • 蛋白名称

    Tryptase alpha/beta-1 (Tryptase-1) (Tryptase I) (Tryptase alpha-1)

  • Organism-1

    Human

  • 基因ID-1

    7177

  • SwissProt-1

    Q15661

  • 背景

    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene

  • 细胞定位

    Cytoplasmic