Myelin Basic Protein(MBP) (ABT-MBP) Mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602081

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商品描述
  • 靶点-Target

    MBP

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    33kD

  • MW(Observed)

    33kD

  • 推荐稀释比

    IHC 1:200-400;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-MBP

  • 免疫原

    Synthesized peptide derived from human Myelin Basic Protein(MBP) AA range: 150-250

  • 特异性

    The antibody can specifically recognize human Myelin Basic Protein.

  • 基因名称

    MBP

  • 蛋白名称

    Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)

  • Organism-1

    Human

  • 基因ID-1

    4155

  • SwissProt-1

    P02686

  • 背景

    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that

  • 细胞定位

    Cytoplasmic