Myelin Basic Protein(MBP) (ABT-MBP) Mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2602081
- 产品信息
商品描述
靶点-Target
MBP
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
33kD
MW(Observed)
33kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-MBP
免疫原
Synthesized peptide derived from human Myelin Basic Protein(MBP) AA range: 150-250
特异性
The antibody can specifically recognize human Myelin Basic Protein.
基因名称
MBP
蛋白名称
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
Organism-1
Human
基因ID-1
4155
SwissProt-1
P02686
背景
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that
细胞定位
Cytoplasmic





