Thyroglobulin (PT0653) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

一键复制产品信息
产品规格:
  • 50μL
货号:

FAB2602059

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Thyroglobulin

  • 反应性

    Human,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    305kD

  • 推荐稀释比

    IHC 1:200-400;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0653

  • 免疫原

    Synthesized peptide derived from human Thyroglobulin AA range: 2700-2768

  • 特异性

    The antibody can specifically recognize human Thyroglobulin protein.

  • 基因名称

    TG

  • 蛋白名称

    Thyroglobulin

  • 别名

    Thyroglobulin;Tg;

  • Organism-1

    Human

  • 基因ID-1

    7038

  • SwissProt-1

    P01266

  • 背景

    Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009],

  • 细胞定位

    Cytoplasmic