FGF-2 Polyclonal Antibody
¥680.00
MutS Protein Homolog 6(MSH6) (ABT-MSH6) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
一键复制产品信息
产品规格：
- 50μL
货号：
FAB2602048
- 产品信息
商品描述
靶点-Target
MSH6
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
153kD
MW(Observed)
180kD
推荐稀释比
IHC 1:50-100;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-MSH6
免疫原
Synthesized peptide derived from human MutS Protein Homolog 6(MSH6) AA range: 900-1000
特异性
The antibody can specifically recognize human MSH6 protein.
基因名称
MSH6 GTBP
蛋白名称
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160)
Organism-1
Human
基因ID-1
2956
SwissProt-1
P52701
背景
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013],
细胞定位
Nuclear
