Insulin (PT0156) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602045

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商品描述
  • 靶点-Target

    Insulin

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    12kD

  • MW(Observed)

    9kD

  • 推荐稀释比

    IHC 1:200-400;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0156

  • 免疫原

    Synthesized peptide derived from human Insulin AA range: 25-110

  • 特异性

    The antibody can specifically recognize human Insulin protein.

  • 基因名称

    INS

  • 蛋白名称

    Insulin

  • 别名

    Insulin [Cleaved into: Insulin B chain;Insulin A chain]

  • Organism-1

    Human

  • 基因ID-1

    3630

  • SwissProt-1

    P01308

  • 背景

    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

  • 细胞定位

    Cytoplasmic