- 产品信息
商品描述
靶点-Target
KSP-Cadherin
反应性
Human,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
90kD
推荐稀释比
IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CDH16
免疫原
Synthesized peptide derived from human KSP-Cadherin AA range:1-100
特异性
This antibody detects endogenous levels of KSP-Cadherin protein.
基因名称
CDH16 UNQ695/PRO1340
蛋白名称
KSP-Cadherin
别名
Cadherin-16;Kidney-specific cadherin;Ksp-cadherin;
Organism-1
Human
基因ID-1
1014
SwissProt-1
O75309
背景
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],
细胞定位
Membranous





