FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Fascin
反应性
Human,Mouse,Rat,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
55kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-FASN
免疫原
Synthesized peptide derived from human Fascin AA range: 250-350
特异性
The antibody can specifically recognize human Fascin protein.
基因名称
FSCN1 FAN1 HSN SNL
蛋白名称
Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
Organism-1
Human
基因ID-1
6624
SwissProt-1
Q16658
背景
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],
细胞定位
Cytoplasmic
