- 产品信息
商品描述
靶点-Target
Cytokeratin 1
反应性
Human,
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CK1
免疫原
Synthesized peptide derived from human Cytokeratin 1 AA range: 200-300
特异性
The antibody can specifically recognize human CK1 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels only skin epidermal cells, whereas squamous or glandular epithelium cells are not labeled.
基因名称
KRT1 KRTA
蛋白名称
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Organism-1
Human
基因ID-1
3848
SwissProt-1
P04264
背景
keratin 1(KRT1) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic, Membranous





