Cytokeratin 1 (ABT-CK1) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602029

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商品描述
  • 靶点-Target

    Cytokeratin 1

  • 反应性

    Human,

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    66kD

  • 推荐稀释比

    IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-CK1

  • 免疫原

    Synthesized peptide derived from human Cytokeratin 1 AA range: 200-300

  • 特异性

    The antibody can specifically recognize human CK1 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels only skin epidermal cells, whereas squamous or glandular epithelium cells are not labeled.

  • 基因名称

    KRT1 KRTA

  • 蛋白名称

    Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)

  • Organism-1

    Human

  • 基因ID-1

    3848

  • SwissProt-1

    P04264

  • 背景

    keratin 1(KRT1) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasmic, Membranous