FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD45
反应性
Human,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Observed)
200kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CD45
免疫原
Synthesized peptide derived from human CD45 (LCA) AA range: 500-600
特异性
The antibody can specifically recognize human CD45 protein, including CD45RA, CD45RB and CD45RO.
基因名称
PTPRC CD45
蛋白名称
Receptor-type tyrosine-protein phosphatase C (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Organism-1
Human
基因ID-1
5788
SwissProt-1
P08575-3
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc
细胞定位
Membranous
