- 产品信息
商品描述
靶点-Target
HDAC6
反应性
Human,Mouse,
应用
IHC,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
131kD
MW(Observed)
130180kD
推荐稀释比
IHC 1:200-400;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-HDAC6
免疫原
Synthesized peptide derived from human HDAC6 AA range: 1100-1215
特异性
The antibody can specifically recognize human HDAC6 protein.
基因名称
HDAC6 KIAA0901 JM21
蛋白名称
Histone deacetylase 6 (HD6) (EC 3.5.1.98)
Organism-1
Human
基因ID-1
10013
SwissProt-1
Q9UBN7
背景
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic





