TGF β Receptor I (ABT-TGFR1) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2602000

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商品描述
  • 靶点-Target

    TGF β Receptor I

  • 反应性

    Human,Mouse,Rat,Bovin,

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    55kD

  • MW(Observed)

    55kD

  • 推荐稀释比

    IHC 1:50-200;IF 1:50-200;ELISA 1:500-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-TGFR1

  • 免疫原

    Synthesized peptide derived from human TGF β Receptor I AA range: 34-100

  • 特异性

    This antibody detects endogenous levels of TGF β Receptor I protein.

  • 基因名称

    TGFBR1 ALK5 SKR4

  • 蛋白名称

    TGF-beta receptor type-1 (TGFR-1) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)

  • Organism-1

    Human

  • 基因ID-1

    7046

  • SwissProt-1

    P36897

  • 背景

    The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

  • 细胞定位

    Membranous