TGF β Receptor I (ABT-TGFR1) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2602000
- 产品信息
商品描述
靶点-Target
TGF β Receptor I
反应性
Human,Mouse,Rat,Bovin,
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
55kD
MW(Observed)
55kD
推荐稀释比
IHC 1:50-200;IF 1:50-200;ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-TGFR1
免疫原
Synthesized peptide derived from human TGF β Receptor I AA range: 34-100
特异性
This antibody detects endogenous levels of TGF β Receptor I protein.
基因名称
TGFBR1 ALK5 SKR4
蛋白名称
TGF-beta receptor type-1 (TGFR-1) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Organism-1
Human
基因ID-1
7046
SwissProt-1
P36897
背景
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
细胞定位
Membranous





