TGF β Receptor II (ABT-TGFR2) mouse mAb一抗

靶点-Target
TGF β Receptor II
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
64kD
MW(Observed)
80kD
推荐稀释比
IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-TGFR2
免疫原
Synthesized peptide derived from human TGF β Receptor II AA range: 100-200
特异性
This antibody detects endogenous levels of TGF β Receptor II protein.
基因名称
TGFBR2
蛋白名称
TGF β Receptor II
Organism-1
Human
基因ID-1
7048
SwissProt-1
P37173
背景
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Membranous

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TGF β Receptor II (ABT-TGFR2) mouse mAb