Myosin Heavy Chain, Smooth Muscle (ABT-SMH) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601964

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商品描述
  • 靶点-Target

    Myosin Heavy Chain_Smooth Muscle

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    227kD

  • MW(Observed)

    227kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-SMH

  • 免疫原

    Synthesized peptide derived from human Myosin Heavy Chain, Smooth Muscle AA range: 300-400

  • 特异性

    This antibody detects endogenous levels of Myosin-11 protein.

  • 基因名称

    MYH11 KIAA0866

  • 蛋白名称

    Myosin Heavy Chain, Smooth Muscle

  • 别名

    Myosin-11;Myosin heavy chain 11;Myosin heavy chain, smooth muscle isoform;SMMHC;

  • Organism-1

    Human

  • 基因ID-1

    4629

  • SwissProt-1

    P35749

  • 背景

    The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alter

  • 细胞定位

    Cytoplasmic