- 产品信息
商品描述
靶点-Target
Mesothelin
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
69kD
MW(Observed)
65kD,45kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-MSLN
免疫原
Synthesized peptide derived from human Mesothelin AA range: 400-500
特异性
This antibody detects endogenous levels of Mesothelin protein.
基因名称
MSLN MPF
蛋白名称
Mesothelin
别名
Mesothelin;CAK1 antigen;Pre-pro-megakaryocyte-potentiating factor;[Cleaved into: Megakaryocyte-potentiating factor;MPF;Mesothelin, cleaved form]
Organism-1
Human
基因ID-1
10232
SwissProt-1
Q13421
背景
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
细胞定位
Cytoplasmic, Membranous





