- 产品信息
商品描述
靶点-Target
INI-1
反应性
Human,Mouse,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
44kD
MW(Observed)
44kD
推荐稀释比
IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-INI1
免疫原
Synthesized peptide derived from human INI-1 AA range: 300-385
特异性
The antibody can specifically recognize human INI-1 protein, including INI-1A and INI-1B. In western blotting of Hela and LnCap cell lysates, the antibody can label two bands with molecular weight of 44, 43 kDa representing INI-1A and INI-1B respectively.
基因名称
SMARCB1 BAF47 INI1 SNF5L1
蛋白名称
INI-1
Organism-1
Human
基因ID-1
6598
SwissProt-1
Q12824
背景
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015],
细胞定位
Nuclear





