AMACR (ABT-AMACR) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601939

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商品描述
  • 靶点-Target

    AMACR

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    42kD

  • MW(Observed)

    42kD

  • 推荐稀释比

    IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-AMACR

  • 免疫原

    Synthesized peptide derived from human AMACR AA range: 300-382

  • 特异性

    The antibody can specifically recognize human AMACR protein. In western blotting of Hela and LnCap cell lysates, the antibody can label a 42 kDa band corresponding to AMACR.

  • 基因名称

    AMACR

  • 蛋白名称

    AMACR

  • 别名

    2 arylpropionyl CoA epimerase;2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha methylacyl Coenzyme A racemase;Alpha methylacyl-CoA racemase deficiency, included;Alpha-methylacyl-CoA racemase;Amacr;AMACR deficiency, included;AMACR_HUMAN;CBAS4;Da1-8;Macr1;Methylacyl CoA racemase alpha;RACE;RM

  • Organism-1

    Human

  • 基因ID-1

    23600

  • SwissProt-1

    Q9UHK6

  • 背景

    AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β-oxidation of branched-chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.

  • 细胞定位

    Cytoplasmic