- 产品信息
商品描述
靶点-Target
AMACR
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
42kD
MW(Observed)
42kD
推荐稀释比
IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-AMACR
免疫原
Synthesized peptide derived from human AMACR AA range: 300-382
特异性
The antibody can specifically recognize human AMACR protein. In western blotting of Hela and LnCap cell lysates, the antibody can label a 42 kDa band corresponding to AMACR.
基因名称
AMACR
蛋白名称
AMACR
别名
2 arylpropionyl CoA epimerase;2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha methylacyl Coenzyme A racemase;Alpha methylacyl-CoA racemase deficiency, included;Alpha-methylacyl-CoA racemase;Amacr;AMACR deficiency, included;AMACR_HUMAN;CBAS4;Da1-8;Macr1;Methylacyl CoA racemase alpha;RACE;RM
Organism-1
Human
基因ID-1
23600
SwissProt-1
Q9UHK6
背景
AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β-oxidation of branched-chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.
细胞定位
Cytoplasmic





