FGF-2 Polyclonal Antibody
¥680.00
Cytokeratin 19&10 (ABT-CK19) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601934
- 产品信息
商品描述
靶点-Target
Cytokeratin 19/10
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
44kD
MW(Observed)
44kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CK19
免疫原
Synthesized peptide derived from human Cytokeratin 19 AA range: 200-300
特异性
The antibody can recognize human CK10 and CK19 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 13, 14, 15, 17, 18, 20.
基因名称
KRT19 KRT10
蛋白名称
Keratin, type I cytoskeletal 19/10 (Cytokeratin-19/10) (CK-19/10) (Keratin-19/10) (K19/10)
别名
40 kDa keRatin intermediate filament;CK 19;CK-19;CK19;Cytokeratin 19;CytokeRatin-19;K19;K1C19_HUMAN;K1CS;KeRatin 19;KeRatin type I 40 kD;KeRatin type I 40kD;KeRatin type I cytoskeletal 19;KeRatin, type I cytoskeletal 19;KeRatin, type I, 40 kd;KeRatin-19;KRT19;MGC15366
Organism-1
Human
基因ID-1
3880
SwissProt-1
P08727;P13645
背景
CK19 is the smallest keratin with a molecular weight of 40-44 kDa. which is widely distributed in monolayer epithelial cells and many squamous epithelial tissues, and plays an important role in maintaining cell structure and morphology. Its function is related to cell proliferation, differentiation, invasion and metastasis, and cell cycle, etc. CK19 is an important biomarker of breast cancer cells, lymph nodes, peripheral blood and bone marrow tumor cells. The keratin of CK10 with molecular weight of about 60kD is not expressed in epidermal basal cells under normal conditions. When the cells generated by basal cell division undergo neoplasia, CK1 / CK10 begins to be expressed. The expression of CK10 is correlated with the differentiation degree of malignant keratinocytes, and the higher the positive expression in tissues, the stronger the differentiation represented by CK10.
细胞定位
Cytoplasmic, Membranous
