COX-2 (ABT-COX2) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601914

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商品描述
  • 靶点-Target

    COX2

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    69kD

  • MW(Observed)

    70kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-COX2

  • 免疫原

    Synthesized peptide derived from human COX-2 (cyclooxygenase-2) AA range: 500-604

  • 特异性

    The antibody can specifically recognize human COX-2 protein. In western blotting of Hela and A549 cell lysates, the antibody can label a 70 kDa band corresponding to COX-2.

  • 基因名称

    PTGS2 COX2

  • 蛋白名称

    Prostaglandin G/H synthase 2 (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)

  • 别名

    COX 2;COX-2;COX2;Cyclooxygenase 2;Cyclooxygenase 2b;Cyclooxygenase;Cyclooxygenase-2;Cyclooxygenase2;fj02a10;Glucocorticoid-regulated inflammatory cyclooxygenase;Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase;GRIPGHS;hCox 2;Macrophage activation-associated marker protein P71/73;OTTHUMP00000033524;PES-2;PGG/HS;PGH synthase 2;PGH2_HUMAN;PGHS 2;PGHS-2;PGHS2;PHS 2;PHS II;PHS2;Prostaglandin endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin endoperoxide synthase 2;Prostaglandin G/H synthase 2;Prostaglandin G/H synthase 2 precursor;Prostaglandin G/H synthase and cyclooxygenase;Prostaglandin G/H synthase;Prostaglandin H2 synthase 2;prostaglandin-endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin-endoperoxide synthase 2;PTGS2;ptgs2a;TIS10;TIS10 protein;unp1239;wu:fj02a10

  • Organism-1

    Human

  • 基因ID-1

    5743

  • SwissProt-1

    P35354

  • 背景

    COX has two isomeric forms of COX-1 and COX-2. It is a membrane-bound protease involved in the conversion of arachidonic acid to prostaglandins. COX-2 is an inducible enzyme that participates in the expression of cell growth factors, tumor promoting factors and cytokines, and is highly expressed in breast, lung, and colon cancers. It is mainly used in tumor research and is one of the targets of tumor therapy.

  • 细胞定位

    Cytoplasmic