- 产品信息
商品描述
靶点-Target
COX2
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
69kD
MW(Observed)
70kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-COX2
免疫原
Synthesized peptide derived from human COX-2 (cyclooxygenase-2) AA range: 500-604
特异性
The antibody can specifically recognize human COX-2 protein. In western blotting of Hela and A549 cell lysates, the antibody can label a 70 kDa band corresponding to COX-2.
基因名称
PTGS2 COX2
蛋白名称
Prostaglandin G/H synthase 2 (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
别名
COX 2;COX-2;COX2;Cyclooxygenase 2;Cyclooxygenase 2b;Cyclooxygenase;Cyclooxygenase-2;Cyclooxygenase2;fj02a10;Glucocorticoid-regulated inflammatory cyclooxygenase;Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase;GRIPGHS;hCox 2;Macrophage activation-associated marker protein P71/73;OTTHUMP00000033524;PES-2;PGG/HS;PGH synthase 2;PGH2_HUMAN;PGHS 2;PGHS-2;PGHS2;PHS 2;PHS II;PHS2;Prostaglandin endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin endoperoxide synthase 2;Prostaglandin G/H synthase 2;Prostaglandin G/H synthase 2 precursor;Prostaglandin G/H synthase and cyclooxygenase;Prostaglandin G/H synthase;Prostaglandin H2 synthase 2;prostaglandin-endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin-endoperoxide synthase 2;PTGS2;ptgs2a;TIS10;TIS10 protein;unp1239;wu:fj02a10
Organism-1
Human
基因ID-1
5743
SwissProt-1
P35354
背景
COX has two isomeric forms of COX-1 and COX-2. It is a membrane-bound protease involved in the conversion of arachidonic acid to prostaglandins. COX-2 is an inducible enzyme that participates in the expression of cell growth factors, tumor promoting factors and cytokines, and is highly expressed in breast, lung, and colon cancers. It is mainly used in tumor research and is one of the targets of tumor therapy.
细胞定位
Cytoplasmic





