FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cytokeratin 8
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
54kD
MW(Observed)
54kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT534
免疫原
Synthesized peptide derived from human Cytokeratin 8 AA range: 400-483
特异性
The antibody can specifically recognize human CK8 protein, and shows no cross reaction with CK1, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20.
基因名称
KRT8 CYK8
蛋白名称
CARD2;CK 8;CK-8;CK8;CYK8;CYKER;Cytokeratin endo A;Cytokeratin-8;DreK8;EndoA;K2C8;K2C8_HUMAN;K8;Keratin 8;Keratin type II cytoskeletal 8;Keratin, type II cytoskeletal 8;Keratin-8;KO;Krt 2.8;KRT8;MGC118110;MGC174782;MGC53564;MGC85764;sb:cb186;Type-II keratin Kb8
别名
CARD2;CK 8;CK-8;CK8;CYK8;CYKER;Cytokeratin endo A;CytokeRatin-8;DreK8;EndoA;K2C8;K2C8_HUMAN;K8;KeRatin 8;KeRatin type II cytoskeletal 8;KeRatin, type II cytoskeletal 8;KeRatin-8;KO;Krt 2.8;KRT8;MGC118110;MGC174782;MGC53564;MGC85764;sb:cb186;Type-II keRatin Kb8
Organism-1
Human
基因ID-1
3856
SwissProt-1
P05787
Organism-2
Mouse
SwissProt-2
P11679
Organism-3
Rat
SwissProt-3
Q10758
背景
Cytokeratin 8 (CK8) is a member of the type II family of cytokeratins with a molecular weight of 53 kDa which plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. It generally exists in monolayer and pseudostratified epithelium, and is expressed in glandular epithelium, transitional epithelium and hepatocytes. It is absent in squamous cell carcinomas. CK8 dimerizes with CK18 to form an intermediate filament in simple single-layered epithelial cells. CK8/18 expression patterns are useful for classification of tumors of unknown origin and poorly differentiated carcinomas.
细胞定位
Cytoplasmic, Membranous
