- 产品信息
商品描述
靶点-Target
Cytokeratin 7
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
51kD
MW(Observed)
51kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT436
免疫原
Synthesized peptide derived from human Cytokeratin 7 AA range: 350-469
特异性
The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the antibody can label a 51 kDa band corresponding to CK7 in A549 and Hela cell lysates.
基因名称
KRT7 SCL
蛋白名称
CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
别名
CK 7;CK-7;CK7;Cytokeratin 7;CytokeRatin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;KeRatin 7;KeRatin 7, type II;KeRatin type II cytoskeletal 7;KeRatin, 55K type II cytoskeletal;KeRatin, simple epithelial;KeRatin, simple epithelial type I, K7;KeRatin, type II cytoskeletal 7;KeRatin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keRatin K7;Type-II keRatin Kb7
Organism-1
Human
基因ID-1
3855
SwissProt-1
P08729
Organism-2
Mouse
SwissProt-2
Q9DCV7
Organism-3
Rat
SwissProt-3
Q6IG12
背景
CK7 is a cytokeratin with a molecular weight of 54 kDa, which mainly marks glandular epithelium and transitional epithelium. It was positive in the epithelium of breast, thyroid, ovary, endometrium and lung, but negative in the epithelium of gastrointestinal tract, colon and prostate. It is mainly used for the study of epithelial tumors. It is often used in combination with CK20 for differential diagnosis of gastrointestinal adenocarcinoma, lung adenocarcinoma and breast cancer, and combined with EMA for diagnosis of synovial sarcoma.
细胞定位
Cytoplasmic, Membranous





