- 产品信息
商品描述
靶点-Target
Cytokeratin 5
反应性
Human,Dog,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
62kD
MW(Observed)
62kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT051
免疫原
Synthesized peptide derived from human Cytokeratin 5 AA range: 500-590
特异性
The antibody can specifically recognize human CK5 protein, and shows no cross reaction with CK6. In western blotting of A431, A549 and Hela cell lysates, the antibody can label a 58 kDa band corresponding to CK5 only in A431 cell lysates.
基因名称
KRT5
蛋白名称
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
别名
58 kDa cytokeRatin;CK-5;CK5;CytokeRatin-5;CytokeRatin5;DDD;DDD1;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;keRatin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;KeRatin 5;KeRatin;keRatin complex 2, basic, gene 5;keRatin, type II cytoskeletal 5;KeRatin-5;KeRatin5;KRT 5;Krt5;KRT5A;type II cytoskeletal 5;Type-II keRatin Kb5
Organism-1
Human
基因ID-1
3852
SwissProt-1
P13647
背景
CK5 is a cytokeratin with a molecular weight of 58 kDa. In normal tissues, CK5 is expressed in squamous epithelium, germinal layer cells of some squamous epithelium, basal cells of ductal epithelium, myoepithelial cells and mesothelial cells, and almost no expression in most glandular epithelial cells. Therefore, it can be used for the differential diagnosis of squamous cell carcinoma and adenocarcinoma, mesothelioma and adenocarcinoma, as well as benign and malignant tumors of prostate, breast and salivary gland epithelium.
细胞定位
Cytoplasmic, Membranous





