- 产品信息
商品描述
靶点-Target
Cytokeratin 14
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
52kD
MW(Observed)
53kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1674
免疫原
Synthesized peptide derived from human Cytokeratin 14 AA range: 400-472
特异性
The antibody can specifically recognize human CK14 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels the basal cell of squamous epithelial cells and glandular epithelia, myoepithelium and mesothelial cells.
基因名称
KRT14
蛋白名称
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)
别名
CK 14;CK-14;ck14;Cytokeratin 14;CytokeRatin-14;CytokeRatin14;Dowling Meara;EBS3;EBS4;Epidermolysis bullosa simplex;K14;K1C14_HUMAN;KeRatin 14;epidermolysis bullosa simplex, Dowling-Meara, Koebner;KeRatin 14;KeRatin;KeRatin type I cytoskeletal 14;KeRatin, type I cytoskeletal 14;KeRatin-14;KeRatin14;Koebner;Krt 14;Krt14;NFJ;OTTHUMP00000164624;type I cytoskeletal 14
Organism-1
Human
基因ID-1
3861
SwissProt-1
P02533
背景
CK14 is a member of the Type I family of cytokeratins with a molecular weight of 50 kDa, which is expressed in the basal cells of myoepithelium and keratinized squamous epithelium. It is mainly used for the difference between stratified squamous epithelium and monolayer epithelium and the diagnosis of squamous cell carcinoma. Eosinophilic tumors at multiple anatomical sites express CK14, which can be used to distinguish from adenocarcinoma, invasive ductal carcinoma of salivary gland and intraductal carcinoma.
细胞定位
Cytoplasmic, Membranous





