- 产品信息
商品描述
靶点-Target
NKX3.1
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
26kD
MW(Observed)
32kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT267
免疫原
Synthesized peptide derived from human protein. AA range:1-100
特异性
The antibody can specifically recognize human NKX3.1 protein.
基因名称
NKX3-1
蛋白名称
Homeobox protein Nkx-3.1
别名
BAPX 2;BAPX2;Homeobox protein NK-3 homolog A;Homeobox protein Nkx 3.1;Homeobox protein Nkx-3.1;Homeobox protein Nkx3.1;NK homeobox;Drosophila;family 3 A;NK homeobox family 3 A;NK homeobox, family 3, member A;NK3 homeobox 1;NK3 transcription factor homolog A;NK3 transcription factor related locus 1;NKX 3;Nkx 3.1;NKX 3A;NKX3 1;NKX3;Nkx3-1;NKX3.1;Nkx3.1, Mouse, homolog of;NKX31_HUMAN;NKX3A
Organism-1
Human
基因ID-1
4824
SwissProt-1
Q99801
Organism-2
Mouse
SwissProt-2
P97436
背景
NKX3.1 is a nuclear transcription factor and a negative regulator of the growth of prostatic epithelial cells. Its mRNA transcription level is regulated by androgens and plays an important role in the occurrence and differentiation of prostate organs and the maintenance of the function of mature organs. NKX3.1 has high sensitivity and specificity in benign prostatic hyperplasia and prostate cancer, and can be used as one of the specific markers to distinguish prostate cancer, benign prostatic hyperplasia and non prostate cancer. It is also expressed in mucous glands of testis, ureter and pulmonary bronchus.
细胞定位
Nuclear





