FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MDR1
反应性
Human,Mouse,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
141kD
MW(Observed)
120kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT252
免疫原
Synthesized peptide derived from human MDR1 AA range: 600-700
特异性
The antibody can specifically recognize human MDR1 protein.
基因名称
ABCB1 MDR1 PGY1
蛋白名称
ABC20;ABCB1;ATP binding cassette, sub family B (MDR/TAP), member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1
别名
ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1
Organism-1
Human
基因ID-1
5243
SwissProt-1
P08183
Organism-3
Rat
SwissProt-3
P43245
背景
MDR-1, also known as P-170, is a membrane glycoprotein encoded by MDR gene. Its main function is to quickly pump cytotoxic drugs out of cells by ATP. Its expression level is related to the permeability of cell membrane, intracellular drug concentration and the degree of drug resistance. It is mainly used in the study of tumor drug resistance.
细胞定位
Membranous
