TCL1 (ABT234) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

一键复制产品信息
产品规格:
  • 50μL
货号:

FAB2601882

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    TCL1

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    13kD

  • MW(Observed)

    13kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT234

  • 免疫原

    Synthesized peptide derived from human TCL1 AA range: 50-114

  • 特异性

    The antibody can specifically recognize human TCL1 protein.

  • 基因名称

    TCL1A TCL1

  • 蛋白名称

    TCL1

  • 别名

    Anti TCL1A;Lymphoma/leukemia, T-cell;Oncogene TCL-1;Oncogene TCL1;P14 TCL1;P14 TCL1 protein;Protein p14 TCL1;T cell leukemia 1;T cell lymphoma 1;T cell lymphoma 1A;T-cell leukemia/lymphoma 1A;T-cell leukemia/lymphoma protein 1A;TCL 1 protein;TCL1;TCL1 oncogene;TCL1 PEN;Tcl1a;TCL1A;TCL1A_HUMAN

  • Organism-1

    Human

  • 基因ID-1

    8115

  • SwissProt-1

    P56279

  • 背景

    TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.

  • 细胞定位

    Cytoplasmic, Nuclear