- 产品信息
商品描述
靶点-Target
Prostate-Specific Membrane Antigen (PSMA)
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
84kD
MW(Observed)
110kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-PSMA
免疫原
Synthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA) AA range: 100-200
特异性
The antibody can specifically recognize human PSMA protein. In western blotting of LnCap, Hela and MCF7 cell lysates, the antibody can label a specific band corresponding to PSMA only in LnCap cell lysates.
基因名称
FOLH1 FOLH NAALAD1 PSM PSMA GIG27
蛋白名称
Glutamate carboxypeptidase 2 (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)
别名
Cell growth inhibiting protein 27;Cell growth-inhibiting gene 27 protein;FGCP;Folate hydrolase;prostate-specific membrane antigen;1;Folate hydrolase 1;Folate hydrolase;Folate hydrolase prostate specific membrane antigen 1;FOLH 1;FOLH;Folh1;FOLH1_HUMAN;Folylpoly gamma glutamate carboxypeptidase;Folylpoly-gamma-glutamate carboxypeptidase;GCP 2;GCP II;GCP2;GCPII;GIG27;Glutamate carboxylase II;Glutamate carboxypeptidase 2;Glutamate carboxypeptidase II;Membrane glutamate carboxypeptidase;mGCP;N acetylated alpha linked acidic dipeptidase 1;N-acetylated-alpha-linked acidic dipeptidase I;NAALAD 1;NAALAD1;NAALAdase;NAALADase I;Prostate specific membrane antigen;Prostate specific membrane antigen variant F;Prostate-specific membrane antigen;PSM;PSMA;Pteroylpoly gamma glutamate carboxypeptidase;Pteroylpoly-gamma-glutamate carboxypeptidase
Organism-1
Human
基因ID-1
2346
SwissProt-1
Q04609
背景
PSMA is a 110 kDa type II transmembrane protein. The gene is located in 11q and is expressed in normal and neoplastic prostate epithelium, as well as in breast, duodenum, colonic mucosa, kidney and tumors of its origin. The expression of PSMA increased after cell carcinogenesis, which was positively correlated with tumor grade and hormone resistance. Combined with PSA can improve the diagnosis of prostate cancer metastasis.
细胞定位
Cytoplasmic, Membranous





