- 产品信息
商品描述
靶点-Target
PD1
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
32kD
MW(Observed)
56kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-PD1
免疫原
Synthesized peptide derived from human PD-1 AA range: 1-100
特异性
The antibody can specifically recognize human PD-1 protein.
基因名称
PDCD1 PD1
蛋白名称
Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)
别名
CD279;CD279 antigen;hPD 1;hPD l;hPD-1;hSLE1;PD 1;PD-1;PD1;PDCD 1;PDCD1;PDCD1_HUMAN;Programmed cell death 1;Programmed cell death 1 protein;Programmed cell death protein 1;Protein PD 1;Protein PD-1;SLEB2;Systemic lupus erythematosus susceptibility 2
Organism-1
Human
基因ID-1
5133
SwissProt-1
Q15116
背景
Programmed death-1 (PD-1) is an important immunosuppressive molecule. It is a member of CD28 superfamily. It is mainly expressed in germinal center related helper T cells and CD8 positive T cells. It includes tyrosine based inhibitory motif immune receptors, and plays an important role in peripheral immune tolerance mechanism and autoimmune diseases. PD-1 is a receptor for PD-L1 and PD-L2. Immune regulation targeting PD-1 is of great significance in anti-tumor, anti infection, anti autoimmune diseases and organ transplantation survival.
细胞定位
Membranous, Cytoplasmic





